Microencapsulation is a fast-developing technology that is important for use in a wide range of everyday applications, from self-healing concrete and paints, to targeted drug delivery and cell encapsulation.  One route to achieve microencapsulation is through self-assembly processes within microemulsions, in our case by combining microfluidic droplet-generating techniques with cucurbit[8]uril (CB[8]) host-guest chemistry.

 

Microdroplets can be used as templates for a polymer-based supramolecular network to form, encapsulating the contents in a microcapsule.  Supramolecular network microcapsules have many advantages over traditional microcapsules, such as extremely high mass loading (> 99 wt.%), and access to a wide variety of release mechanisms.

Publications

Controlling Spatiotemporal Mechanics of Supramolecular Hydrogel Networks with Highly Branched Cucurbit[8]uril Polyrotaxanes
CSY Tan, J Liu, AS Groombridge, SJ Barrow, CA Dreiss, OA Scherman
Advanced Functional Materials
(2018)
28
Aqueous interfacial gels assembled from small molecule supramolecular polymers.
AS Groombridge, A Palma, RM Parker, C Abell, OA Scherman
Chemical science
(2017)
8
Microcapsule Buckling Triggered by Compression-Induced Interfacial Phase Change.
AR Salmon, RM Parker, AS Groombridge, A Maestro, RJ Coulston, J Hegemann, J Kierfeld, OA Scherman, C Abell
Langmuir : the ACS journal of surfaces and colloids
(2016)
32
Time-resolved ICP-MS Measurement: a New Method for Elemental and Multiparametric Analysis of Single Cells
S-I Miyashita, AS Groombridge, S-I Fujii, A Takatsu, K Chiba, K Inagaki
Anal Sci
(2014)
30
Highly efficient single-cell analysis of microbial cells by time-resolved inductively coupled plasma mass spectrometry
SI Miyashita, AS Groombridge, SI Fujii, A Minoda, A Takatsu, A Hioki, K Chiba, K Inagaki
J. Anal. At. Spectrom.
(2014)
29
Separation and quantification of RNA molecules using size-exclusion chromatography hyphenated with inductively coupled plasma-mass spectrometry.
S-I Fujii, K Inagaki, S-I Miyashita, AS Groombridge, K Nagasawa, K Chiba, A Takatsu
Electrophoresis
(2014)
35
A novel concentric grid nebulizer for inductively coupled plasma optical emission spectrometry
K Inagaki, SI Fujii, SI Miyashita, K Nagasawa, T Okahashi, AS Groombridge, A Takatsu, K Chiba
Journal of Analytical Atomic Spectrometry
(2014)
29
High sensitive elemental analysis of single yeast cells (saccharomyces cerevisiae) by time-resolved inductively-coupled plasma mass spectrometry using a high efficiency cell introduction system
AS Groombridge, S-I Miyashita, S-I Fujii, K Nagasawa, T Okahashi, M Ohata, T Umemura, A Takatsu, K Inagaki, K Chiba
Anal Sci
(2013)
29
Modified high performance concentric nebulizer for inductively coupled plasma optical emission spectrometry
AS Groombridge, K Inagaki, SI Fujii, K Nagasawa, T Okahashi, A Takatsu, K Chiba
Journal of Analytical Atomic Spectrometry
(2012)
27

Postgraduate student